Understanding Your AMH Test Results: Complete Guide to Ovarian Reserve
AMH (Anti-Müllerian Hormone) measures your egg quantity, not quality. Normal levels range from 1.0-3.5 ng/mL for most women of reproductive age, but "normal" depends on your age. Low AMH doesn't mean you can't get pregnant—it suggests you may respond less robustly to fertility medications and may have fewer years of fertility remaining. High AMH may indicate PCOS or risk of ovarian hyperstimulation during IVF.
Getting your AMH results can feel like receiving a fertility verdict. But before you panic over a number, understand what this test actually measures—and equally important, what it can't tell you.
What Is AMH and Why Does It Matter?
Anti-Müllerian Hormone is a protein produced by the granulosa cells surrounding each developing egg follicle in your ovaries. The more developing follicles you have, the higher your AMH level. This makes AMH a useful marker for estimating your remaining egg supply—your "ovarian reserve."
Unlike FSH and estradiol, which fluctuate throughout your menstrual cycle, AMH remains relatively stable. You can test it any day of your cycle without affecting accuracy, making it a convenient and reliable snapshot of ovarian reserve.
What AMH Tells You
- Approximate egg quantity – How many eggs you have remaining relative to others your age
- Likely response to IVF medications – How many eggs you might retrieve during a cycle
- Potential timeline – Whether menopause might arrive earlier than average
- PCOS indicator – Very high levels often accompany polycystic ovary syndrome
What AMH Cannot Tell You
- Egg quality – The chromosomal health of your eggs (age is the best predictor of quality)
- Whether you can get pregnant – Women with very low AMH conceive naturally every day
- Exactly when menopause will occur – It provides estimates, not certainties
- Your fertility this month – It doesn't predict any single cycle's outcome
AMH Reference Ranges by Age
AMH levels naturally decline with age as your egg supply diminishes. What's "normal" for a 25-year-old differs significantly from what's normal at 40. Here are the typical ranges:
| AMH Level (ng/mL) | Interpretation | IVF Response |
|---|---|---|
| Above 3.5 | High – May indicate PCOS | Risk of overstimulation (OHSS) |
| 1.0 – 3.5 | Normal range | Good expected response |
| 0.5 – 1.0 | Low – Reduced reserve | Fewer eggs expected |
| Below 0.5 | Very low – Significantly reduced | May need higher medication doses |
Typical AMH Levels by Age
Average AMH Decline with Age
These are median values—there's significant individual variation. A 35-year-old with AMH of 1.2 ng/mL is on the lower end but not necessarily facing fertility problems. Context matters enormously.
Interpreting Your Results: What Each Range Means
High AMH (Above 3.5 ng/mL)
Often associated with PCOS or a higher number of developing follicles. Good egg supply, but may indicate anovulation. During IVF, requires careful monitoring to avoid ovarian hyperstimulation syndrome (OHSS). Many women with high AMH conceive naturally once ovulation is regulated.
Normal AMH (1.0-3.5 ng/mL)
Suggests age-appropriate ovarian reserve. Expected to respond well to fertility medications if needed. No immediate concerns about egg supply, though this doesn't guarantee conception. Continue with standard fertility recommendations.
Low AMH (0.5-1.0 ng/mL)
Indicates reduced egg supply relative to age. May suggest fewer fertile years remaining and potentially smaller response to IVF stimulation. Doesn't predict monthly fertility—natural conception still possible. Consider discussing timeline acceleration with your doctor.
Very Low AMH (Below 0.5 ng/mL)
Significantly diminished ovarian reserve. May indicate approaching menopause or primary ovarian insufficiency. IVF may require higher medication doses or multiple cycles. Natural conception becomes less likely but isn't impossible. Earlier intervention typically recommended.
What Low AMH Really Means for Getting Pregnant
Low AMH is not a fertility death sentence—but it is important information. Here's what the research actually shows:
Natural Conception
A landmark 2017 study in JAMA followed women trying to conceive naturally. After 12 months:
- Women with low AMH had similar pregnancy rates to women with normal AMH
- 65% of women with low AMH conceived within a year
- AMH did not predict natural fertility in women under 38 without known fertility issues
The study concluded that AMH levels should not be used to counsel young women about their ability to conceive naturally. Low AMH doesn't mean you're less likely to get pregnant this cycle—it suggests you may have fewer cycles remaining before your supply depletes significantly.
IVF Response
Where AMH becomes highly relevant is predicting IVF outcomes:
- Low AMH (0.5-1.0): May retrieve 5-8 eggs vs. 10-15 with normal AMH
- Very low AMH (<0.5): May retrieve 1-4 eggs, potentially requiring multiple cycles
- Pregnancy per transfer: Similar if good-quality embryos develop—quantity affects how many "tries" you get per cycle
High AMH: When More Isn't Always Better
AMH above 3.5 ng/mL—especially above 5.0—often indicates polycystic ovary syndrome (PCOS). While having abundant eggs sounds positive, high AMH comes with its own considerations:
Potential PCOS Indicators
- Multiple small follicles visible on ultrasound (polycystic-appearing ovaries)
- Irregular or absent periods
- Elevated androgens (acne, excess hair growth)
- Difficulty ovulating regularly
IVF Considerations with High AMH
- OHSS risk: Ovaries may over-respond to medications, causing dangerous fluid shifts
- Lower medication doses: Typically start with minimal stimulation
- Trigger options: May use GnRH agonist trigger instead of hCG to reduce OHSS risk
- Freeze-all protocol: Often recommended to allow hormone levels to normalize before transfer
The good news: Women with high AMH due to PCOS often have excellent success once ovulation is achieved, whether through medication like letrozole or through IVF with appropriate protocols.
Common AMH Misconceptions
AMH predicts egg supply over time, not this month's fertility. Natural conception depends more on ovulation quality, fallopian tube function, and sperm health than on total egg count.
There's no formula converting AMH to remaining eggs. The test measures follicles producing AMH, which reflects but doesn't quantify your true reserve.
You can have normal AMH with blocked tubes, endometriosis, uterine issues, or male factor infertility. AMH doesn't assess overall fertility—just egg quantity.
Some supplements (DHEA, CoQ10) may improve egg quality or response to IVF, but they don't create new eggs. Small fluctuations in AMH readings are normal variation, not real change.
Comprehensive fertility assessment includes AMH, FSH, estradiol, antral follicle count (AFC), thyroid function, semen analysis, and often hysterosalpingogram (HSG) or saline sonogram.
What to Do After Getting Your Results
If Your AMH Is Low
- Don't panic – Low AMH doesn't mean infertility. It's information, not a verdict.
- Get complete testing – AMH alone doesn't tell the full story. Request FSH, AFC, and other baseline tests.
- Consider your timeline – If you're not ready to conceive now, discuss egg or embryo freezing.
- Evaluate lifestyle factors – Smoking, extreme weight, and certain medications can affect AMH. Address modifiable factors.
- Discuss options with a specialist – Reproductive endocrinologists can provide personalized guidance based on your complete picture.
If Your AMH Is Normal
- Continue standard TTC advice – Time intercourse during your fertile window, track ovulation if desired.
- Don't become complacent – Normal AMH doesn't guarantee conception. Age still affects egg quality.
- Seek help after 12 months – Or 6 months if you're 35+. Normal AMH doesn't rule out other fertility factors.
If Your AMH Is High
- Evaluate for PCOS – High AMH often accompanies PCOS. Check for irregular cycles and other symptoms.
- Confirm ovulation – Abundant eggs don't help if you're not ovulating. Track with OPKs or temperature charting.
- Discuss treatment if needed – If you have PCOS with irregular ovulation, medications like letrozole can help.
AMH and Fertility Treatment Decisions
When AMH Influences Treatment Path
Your AMH level may affect which fertility treatment your doctor recommends:
| AMH Level | Treatment Considerations | Protocol Adjustments |
|---|---|---|
| High (>3.5) | Oral medications first; IVF with caution | Low-dose stim, GnRH trigger, freeze-all |
| Normal (1.0-3.5) | Standard approach based on other factors | Conventional protocols typically appropriate |
| Low (0.5-1.0) | May move to IVF sooner; time is a factor | Higher doses, consider mini-IVF or banking |
| Very Low (<0.5) | IVF often recommended quickly; discuss donor eggs | Maximum protocols, multiple retrievals |
The Antral Follicle Count Connection
AMH and antral follicle count (AFC) measure similar things differently. AFC counts visible follicles via ultrasound at cycle start. When AMH and AFC align, confidence in the assessment is high. When they disagree, doctors typically rely more heavily on AFC for IVF dosing decisions.
- Low AMH + Low AFC: Confirms diminished ovarian reserve
- Low AMH + Normal AFC: May have better response than AMH suggests
- Normal AMH + Low AFC: AFC may be more predictive of cycle response
Can You Improve AMH Levels?
You cannot create new eggs or reverse ovarian aging. However, some factors may influence AMH readings:
Factors That May Lower AMH
- Smoking (accelerates egg loss and lowers AMH)
- Ovarian surgery (especially for endometriomas)
- Chemotherapy or radiation
- Vitamin D deficiency (may artificially suppress readings)
- Hormonal contraceptives (may slightly lower values)
What Research Shows About Supplements
- DHEA: Some studies suggest improved IVF response in low-reserve patients, but doesn't increase true AMH
- CoQ10: May support egg quality and mitochondrial function; no proven effect on AMH
- Vitamin D: Correcting deficiency may normalize artificially low readings
When to Retest AMH
Because AMH declines naturally with age, retesting makes sense in certain situations:
- Before starting fertility treatment – Confirm current status if last test was 6+ months ago
- After lifestyle changes – If you quit smoking or addressed vitamin D deficiency
- Unexpected result – Labs can make errors; retest if result seems inconsistent with your clinical picture
- Before egg freezing – Get current numbers to estimate expected yield
Routine monitoring (e.g., every few months) typically isn't necessary and can cause unnecessary anxiety over normal fluctuations.